PodiTrodi

About

The PodiTrodi project aimed at overcoming the draw-backs of current Point-of-Care tests by developing technologies for really integrated (but low-cost!) sample preparation. To achieve the challenging mission described below, PodiTrodi followed a multidimensional, multi-material system integration approach on four project "levels" (Heterogeneous System Integration, Instrumentation, Manufacturing Infrastructure, Development Infrastructure).

Mission
Create a single self-contained unit, with a human-machine interface, suitable for point-of-care diagnosis of the diseases (e.g Chagas), which integrates several technologies such as heterogeneous Microsystems (biosensors and microfluidics), control electronics, sensor read-out and an embedded processor and power supply.

Why is this important?
The diagnosis and discrimination of infectious diseases (such as dengue, malaria, HIV, chagas) in geographic regions with poor or low-density medical infrastructure is of high socioeconomic importance. While so-called "rapid in-vitro diagnostic (ivD) tests" for single diseases are already on the market, more complex analytical protocols are necessary to clearly identify a certain tropical disease AND to determine the status of the disease - the latter being crucial for proper treatment. Such complex analytical protocols would include liquid handling as well as sample preparation like transcription and amplification (PCR) of the virus` RNA (dengue, HIV) or the parasite (lechimaniasis, malaria, Chagas). These sample preparation steps are currently only available in laboratories and have not yet found their way into mass-producible, integrated point-of-care diagnostic tests. This is where PodiTrodi comes into the story.

Project Timeframe
From 01-09-2011 to 30-11-2014

OBJECTIVES & FOCUS


  • Provide effective analytical and sample preparation tools in a low-cost integrated unit for areas with poor medical infrastructure, which are most affected by tropical diseases.

results achieved


  • Device controlled by a portable instrument including sensor read-out, human-machine interface and embedded processor, suitable for point- of-care diagnosis of Chagas' Disease.

project poster

Poditrodi device

poditrodi presentation 

PROJECT DETAILS

PodiTrodi
Technology Platform for Point-of-care diagnostics for tropical diseases
http://www.poditrodi.org/

PodiTrodi has received funding from the European Union's 7th Framework Programme in the area of EU-Brazil Research.

The Brazilian funding was provided by Brazilian Ministry of Science and Technology and CNPq Conselho Nacional de Desenvolvimento Científico e Tecnológico.

7th Framework Programme Grant agreement no. 287770

Contact

http://www.poditrodi.org/

info@poditrodi.org

EU EUBrasilCloudFORUM is funded by the European Commission under the Cooperation Programme, Horizon 2020 grant agreement No 689495. Este projeto é resultante da 3a Chamada Coordenada BR-UE em Tecnologias da Informação e Comunicação (TIC), anunciada pelo Ministério da Ciência, Tecnologia e Inovação (MCTI), no âmbito to acordo de subvenção Número 689495. Privacy Policy | Disclaimer Terms of use